PUBLICATIONS
2018
2018
Afrin S, Zhang CRC, Meyer C, Stinson CL, Pham T, Bruxner TJC, Venn NC, Trahair TN, Sutton R, Marschalek R, Fink JL, Moore AS (2018). Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in Leukemia. Mol Cancer Res 16: 279-285.
Meyer C, Burmeister T, Gröger D, Tsaur G, Fechina L, Renneville A, Sutton R, Venn NC, Emerenciano M, Pombo-de-Oliveira MS, Barbieri Blunck C, Almeida Lopes B, Zuna J, Trka J, Ballerini P, Lapillonne H, De Braekeleer M, Cazzaniga G, Corral Abascal L, van der Velden VHJ, Delabesse E, Park TS, Oh SH, Silva MLM, Lund-Aho T, Juvonen V, Moore AS, Heidenreich O, Vormoor J, Zerkalenkova E, Olshanskaya Y, Bueno C, Menendez P, Teigler-Schlegel A, Zur Stadt U, Lentes J, Göhring G, Kustanovich A, Aleinikova O, Schäfer BW, Kubetzko S, Madsen HO, Gruhn B, Duarte X, Gameiro P, Lippert E, Bidet A, Cayuela JM, Clappier E, Alonso CN, Zwaan CM, van den Heuvel-Eibrink MM, Izraeli S, Trakhtenbrot L, Archer P, Hancock J, Möricke A, Alten J, Schrappe M, Stanulla M, Strehl S, Attarbaschi A, Dworzak M, Haas OA, Panzer-Grümayer R, Sedek L, Szczepanski T, Caye A, Suarez L, Cave H, Marschalek R (2018). The MLL recombinome of acute leukemias in 2017. Leukemia. 32:273-284
Meyer C, Burmeister T, Gröger D, Tsaur G, Fechina L, Renneville A, Sutton R, Venn NC, Emerenciano M, Pombo-de-Oliveira MS, Barbieri Blunck C, Almeida Lopes B, Zuna J, Trka J, Ballerini P, Lapillonne H, De Braekeleer M, Cazzaniga G, Corral Abascal L, van der Velden VHJ, Delabesse E, Park TS, Oh SH, Silva MLM, Lund-Aho T, Juvonen V, Moore AS, Heidenreich O, Vormoor J, Zerkalenkova E, Olshanskaya Y, Bueno C, Menendez P, Teigler-Schlegel A, Zur Stadt U, Lentes J, Göhring G, Kustanovich A, Aleinikova O, Schäfer BW, Kubetzko S, Madsen HO, Gruhn B, Duarte X, Gameiro P, Lippert E, Bidet A, Cayuela JM, Clappier E, Alonso CN, Zwaan CM, van den Heuvel-Eibrink MM, Izraeli S, Trakhtenbrot L, Archer P, Hancock J, Möricke A, Alten J, Schrappe M, Stanulla M, Strehl S, Attarbaschi A, Dworzak M, Haas OA, Panzer-Grümayer R, Sedek L, Szczepanski T, Caye A, Suarez L, Cave H, Marschalek R (2018). The MLL recombinome of acute leukemias in 2017. Leukemia. 32:273-284
2017
Smith M, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister R, Minden M, Marschalek R, Gingras AC, Hoang T, Ikura M (2017). Evolution of AF6-RAS Association and its Implications in Mixed-Lineage Leukemia. Nat Commun 8, 1099.
Malinowska I, Sikorska-Fic B, Romiszewska M, Stefaniak A, Pastwinska A, Gorska E, Popko K, Meyer C, Marschalek R, Szczepanski T (2017). A Case of Acute Myeloid Leukemia with Novel Translocation t(6;11)(p22.2;q23) and Concurrent Insertion ins(11;9)(q23;p21.3p21.3). Adv Exp Med Biol. 1021, 93-98
Malinowska I, Sikorska-Fic B, Romiszewska M, Stefaniak A, Pastwinska A, Gorska E, Popko K, Meyer C, Marschalek R, Szczepanski T (2017). A Case of Acute Myeloid Leukemia with Novel Translocation t(6;11)(p22.2;q23) and Concurrent Insertion ins(11;9)(q23;p21.3p21.3). Adv Exp Med Biol. 1021, 93-98
2016
Lentes J, Thomay K, Schneider DT, Bernbeck B, Reinhardt D, Marschalek R, Meyer C, Schlegelberger B, Göhring G (2016). Identification of a Cryptic Insertion ins(11;X)(q23;q28q12) Resulting in a KMT2A-FLNA Fusion in a 13-Month-Old Child with Acute Myelomonocytic Leukemia. Cytogenet Genome Res 150:281-286.
Lopes BA, Meyer C, Barbosa TC, Stadt UZ, Horstmann M, Venn NC, Heatley S, White DL, Sutton R, Pombo-de-Oliveira MS, Marschalek R, Emerenciano M (2016). COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia. Oncotarget. 2016 Jul 13. doi: 10.18632/oncotarget.10590. [Epub ahead of print]
Ney Garcia DR, de Souza MT, de Figueiredo AF, Othman MA, Rittscher K, Abdelhay E, Capela de Matos RR, Meyer C, Marschalek R, Land MG, Liehr T, Ribeiro RC, Silva ML (2016). Molecular characterization of KMT2A fusion partner genes in 13 cases of pediatric leukemia with complex or cryptic karyotypes. Hematol Oncol. 2016 Jun 10. doi: 10.1002/hon.2299. [Epub ahead of print]
Marschalek R (2016). Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways. Ann Lab Med 36, 85-100.
Lopes BA, Meyer C, Barbosa TC, Stadt UZ, Horstmann M, Venn NC, Heatley S, White DL, Sutton R, Pombo-de-Oliveira MS, Marschalek R, Emerenciano M (2016). COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia. Oncotarget. 2016 Jul 13. doi: 10.18632/oncotarget.10590. [Epub ahead of print]
Ney Garcia DR, de Souza MT, de Figueiredo AF, Othman MA, Rittscher K, Abdelhay E, Capela de Matos RR, Meyer C, Marschalek R, Land MG, Liehr T, Ribeiro RC, Silva ML (2016). Molecular characterization of KMT2A fusion partner genes in 13 cases of pediatric leukemia with complex or cryptic karyotypes. Hematol Oncol. 2016 Jun 10. doi: 10.1002/hon.2299. [Epub ahead of print]
Marschalek R (2016). Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways. Ann Lab Med 36, 85-100.
2015
Szotkowski T, Jarosova M, Zimmermannova O, Meyer C, Marschalek R, Zuna J, Hubaçek J, Indrak K (2015). Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (MLL-ME2) fusion gene. Cancer Genet 208, 610-614.
Matveeva E, Kazakova A, Olshanskaya Y, Tsaur G, Shelikhova L, Meyer C, Marschalek R, Novichkova G, Maschan M, Maschan A (2015). A new variant of KMT2A(MLL)-FLNA fusion transcript in acute myeloid leukemia with ins(X;11)(q28;q23q23). Cancer Genet 208, 148-51.
Ney Garcia DR, Liehr T, Emerenciano M, Meyer C, Marschalek R, Oliveira MD, Ribeiro RC, Poirot Land MG, Macedo Silva ML (2015). Molecular studies reveal a MLL-MLLT3 gene fusion displaced in a case of childhood acute lymphoblastic leukemia with complex karyotype. Cancer Genet 208, 143-147.
Marschalek R (2015). MLL Leukemia and Future Treatment Strategies. Arch Pharm (Weinheim) 348, 221-228.
Emerenciano M, Barbosa TD, de Almeida Lopes B, Meyer C, Marschalek R, Pombo-de-Oliveira MS (2015). Subclonality and prenatal origin of RAS mutations in KMT2A (MLL)-rearranged infant acute lymphoblastic leukaemia. Br J Haematol 170, 268-271.
Burmeister T, Meyer C, Gröger D, Hofmann J, Marschalek R (2015). Evidence-based RT-PCR methods for the detection of the 8 most common MLL aberrations in acute leukemias. Leuk Res 39, 242-247.
Matveeva E, Kazakova A, Olshanskaya Y, Tsaur G, Shelikhova L, Meyer C, Marschalek R, Novichkova G, Maschan M, Maschan A (2015). A new variant of KMT2A(MLL)-FLNA fusion transcript in acute myeloid leukemia with ins(X;11)(q28;q23q23). Cancer Genet 208, 148-51.
Ney Garcia DR, Liehr T, Emerenciano M, Meyer C, Marschalek R, Oliveira MD, Ribeiro RC, Poirot Land MG, Macedo Silva ML (2015). Molecular studies reveal a MLL-MLLT3 gene fusion displaced in a case of childhood acute lymphoblastic leukemia with complex karyotype. Cancer Genet 208, 143-147.
Marschalek R (2015). MLL Leukemia and Future Treatment Strategies. Arch Pharm (Weinheim) 348, 221-228.
Emerenciano M, Barbosa TD, de Almeida Lopes B, Meyer C, Marschalek R, Pombo-de-Oliveira MS (2015). Subclonality and prenatal origin of RAS mutations in KMT2A (MLL)-rearranged infant acute lymphoblastic leukaemia. Br J Haematol 170, 268-271.
Burmeister T, Meyer C, Gröger D, Hofmann J, Marschalek R (2015). Evidence-based RT-PCR methods for the detection of the 8 most common MLL aberrations in acute leukemias. Leuk Res 39, 242-247.
2014
Douet-Guilbert N, Eveillard JR, Meyer C, Ugo V, Le Bris MJ, Basinko A, Morel F, Marschalek R, De Braekeleer M (2014). MLL partner genes in secondary acute lymphoblastic leukemia: Report of a new partner PRRC1 and review of the literature. Leuk Res 38, 1316-1319.
Ahlmann M, Meyer C, Marschalek R, Burkhardt B, Koehler G, Klapper W, Juergens H, Rössig C (2014). Complex MLL rearrangement in non-infiltrated bone marrow in an infant with stage II precursor B-lymphoblastic lymphoma. Eur J Haematol 93, 349-353.
Pastorczak A, Szczepanski T, Trelinska J, Finalet Ferreiro J, Wlodarska I, Mycko K, Polucha A, Sedek L, Meyer C, Marschalek R, Mynarski W (2014). Secondary acute monocytic leukemia positive for 11q23 rearrangement in Nijmegen breakage syndrome. Pediatr Blood Cancer 61, 1469-1471.
Emerenciano M, Barbosa TC, Lopes BA, Blunck CB, Faro A, Andrade C, Meyer C, Marschalek R, Pombo-de-Oliveira MS (2014). ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia. BMC Cancer 14, 127.
Yang JJ, Park TS, Lee ST, Seo JY, Oh SH, Cho EH, Burmeister T, Ludwig WD, Meyer C, Marschalek R, Kim HJ, Kim SH (2014). Molecular characterization and clinical course of MLL-ACTN4 rearrangement in therapy-related hematologic malignancies. Haematologica 99, e49-51.
Coenen EA, Zwaan CM, Stary J, Baruchel A, de Haas V, Stam RW, Reinhardt D, Kaspers GJ, Arentsen-Peters ST, Meyer C, Marschalek R, Lo Nigro L, Dworzak M, Pieters R, van den Heuvel-Eibrink MM (2014). Unique BHLHB3 overexpression in pediatric acute myeloid leukemia with t(6;11)(q27;q23). Leukemia 28, 1564-1568.
Yang JJ, Park TS, Lee ST, Seo JY, Oh SH, Cho EH, Strehl S, Mühlegger N, Dworzak MN, Zuna J, Pospisilova D, Meyer C, Marschalek R, Kim HJ, Kim SH (2014). Molecular characterization and clinical impact of t(11;15)(q23;q14-15) MLL-CASC5 rearrangement. Haematologica 99, e11-3.
Ahlmann M, Meyer C, Marschalek R, Burkhardt B, Koehler G, Klapper W, Juergens H, Rössig C (2014). Complex MLL rearrangement in non-infiltrated bone marrow in an infant with stage II precursor B-lymphoblastic lymphoma. Eur J Haematol 93, 349-353.
Pastorczak A, Szczepanski T, Trelinska J, Finalet Ferreiro J, Wlodarska I, Mycko K, Polucha A, Sedek L, Meyer C, Marschalek R, Mynarski W (2014). Secondary acute monocytic leukemia positive for 11q23 rearrangement in Nijmegen breakage syndrome. Pediatr Blood Cancer 61, 1469-1471.
Emerenciano M, Barbosa TC, Lopes BA, Blunck CB, Faro A, Andrade C, Meyer C, Marschalek R, Pombo-de-Oliveira MS (2014). ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia. BMC Cancer 14, 127.
Yang JJ, Park TS, Lee ST, Seo JY, Oh SH, Cho EH, Burmeister T, Ludwig WD, Meyer C, Marschalek R, Kim HJ, Kim SH (2014). Molecular characterization and clinical course of MLL-ACTN4 rearrangement in therapy-related hematologic malignancies. Haematologica 99, e49-51.
Coenen EA, Zwaan CM, Stary J, Baruchel A, de Haas V, Stam RW, Reinhardt D, Kaspers GJ, Arentsen-Peters ST, Meyer C, Marschalek R, Lo Nigro L, Dworzak M, Pieters R, van den Heuvel-Eibrink MM (2014). Unique BHLHB3 overexpression in pediatric acute myeloid leukemia with t(6;11)(q27;q23). Leukemia 28, 1564-1568.
Yang JJ, Park TS, Lee ST, Seo JY, Oh SH, Cho EH, Strehl S, Mühlegger N, Dworzak MN, Zuna J, Pospisilova D, Meyer C, Marschalek R, Kim HJ, Kim SH (2014). Molecular characterization and clinical impact of t(11;15)(q23;q14-15) MLL-CASC5 rearrangement. Haematologica 99, e11-3.
2013
Tsaur GA, Popov AM, Plekhanova OM, Kustanovich AM, Aleynikova OV, Gindina TL, Demina AS, Druy AY, Kovalev SY, Kondratchik KY, Misyurin AV, Myakova NV, Riger TO, Savelyev LI, Sokova OI, Streneva OV, Suchkova MV, Finashutina YP, Fleyshman YV, Shorikov YV, Yutskevich RI, Meyer C, Marschalek R, Fechina LG (2013). Translocation t(1;11)(p32;q23) with MLL-EPS15 fusion gene formation in acute leukemias: a review and 6 new case reports. Approaches to minimal residual disease monitoring. Oncohematologia 1,18-33.
Morak M, Meyer C, Marschalek R, Mann G, Haas OA, Panzer-Grümayer R (2013). Clone-specific secondary aberrations are not detected in neonatal blood spots of children with ETV6-RUNX1-positive leukemia. Haematologica 98, e108-110.
Morak M, Meyer C, Marschalek R, Mann G, Haas OA, Panzer-Grümayer R (2013). Clone-specific secondary aberrations are not detected in neonatal blood spots of children with ETV6-RUNX1-positive leukemia. Haematologica 98, e108-110.
Oh SJ, Park TS, Lee JY, Mun YC, Seong CM, Marschalek R, Meyer C, Chung WS, Huh J (2013). Acute Promyelocytic Leukemia with a Rare PML Exon 4/ RARA Exon 3 Fusion Transcript Variant. Acta Haematol 130, 176-180.
Yang JJ, Oh SH, Meyer C, Marschalek R, Park TS (2013). RE: Acute myeloid leukemia associated with FGFR1 abnormalities. Int J Hematol 2013 Jun 7. [Epub ahead of print].
Tuborgh A, Meyer C, Marschalek R, Preiss B, Hasle H, Kjeldsen E (2013). Complex Three-Way Translocation Involving MLL , ELL , RREB1 , and CMAHP Genes in an Infant with Acute Myeloid Leukemia and t(6;19;11)(p22.2;p13.1;q23.3). Cytogenet Genome Res 2013 May 30. [Epub ahead of print].
Launay E, Henry C, Meyer C, Chappe C, Taque S, Boulland ML, Abdelali RB, Dugay F, Marschalek R, Bastard C, Fest T, Gandemer V, Belaud-Rotureau MA (2013). MLL-SEPT5 Fusion Transcript in Infant Acute Myeloid Leukemia with t(11;22)(q23;q11). Leuk Lymphoma 2013 Jun 3. [Epub ahead of print].
Meyer C, Zur Stadt U, Escherich G, Hofmann J, Binato R, Barbosa Tda C, Emerenciano M, Pombo-de-Oliveira MS, Horstmann M, Marschalek R (2013). Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients. Am J Blood Res 3, 165-173.
Meyer C, Hofmann J, Burmeister T, Gröger D, Park TS, Emerenciano M, Pombo de Oliveira M, Renneville A, Villarese P, Macintyre E, Cave H, Clappier E, Mass-Malo K, Zuna J, Trka J, De Braekeleer E, De Braekeleer M, Oh SH, Tsaur G, Fechina L, van der Velden VH, van Dongen JJ, Delabesse E, Binato R, Silva ML, Kustanovich A, Aleinikova O, Harris MH, Lund-Aho T, Juvonen V, Heidenreich O, Vormoor J, Choi WW, Jarosova M, Kolenova A, Bueno C, Menendez P, Wehner S, Eckert C, Talmant P, Tondeur S, Lippert E, Launay E, Henry C, Ballerini P, Lapillone H, Callanan MB, Cayuela JM, Herbaux C, Cazzaniga G, Kakadiya PM, Bohlander S, Ahlmann M, Choi JR, Gameiro P, Lee DS, Krauter J, Cornillet-Lefebvre P, Te Kronnie G, Schäfer BW, Kubetzko S, Alonso CN, Zur Stadt U, Sutton R, Venn NC, Izraeli S, Trakhtenbrot L, Madsen HO, Archer P, Hancock J, Cerveira N, Teixeira MR, Lo Nigro L, Möricke A, Stanulla M, Schrappe M, Sedek L, Szczepanski T, Zwaan CM, Coenen EA, van den Heuvel-Eibrink MM, Strehl S, Dworzak M, Panzer-Grümayer R, Dingermann T, Klingebiel T, Marschalek R (2013). The MLL recombinome of acute leukemias in 2013. Leukemia 2013 Apr 30. doi: 10.1038/leu.2013.135. [Epub ahead of print].
Binato R, Meyer C, Macedo-Silva ML, Garcia D, Figueiredo A, Hofmann J, Vieira TP, Abdelhay E, Marschalek R (2013). Analyzing acute leukemia patients with complex MLL rearrangements by a sequential LDI-PCR approach. Cancer Lett 2013 Apr 2. doi:pii: S0304-3835(13)00271-1. 10.1016/j.canlet.2013.03.029. [Epub ahead of print].
Emerenciano M, Meyer C, Mansur MB, Marschalek R, Pombo-de-Oliveira MS; Brazilian Collaborative Study Group of Infant Acute Leukaemia. The distribution of MLL breakpoints correlates with outcome in infant acute leukaemia. Br J Haematol 161, 224-236.
Emerenciano M, Kowarz E, Karl K, de Almeida Lopes B, Scholz B, Bracharz S, Meyer C, Pombo-de-Oliveira MS, Marschalek R (2013). Functional analysis of the two reciprocal fusion genes MLL-NEBL and NEBL-MLL reveal their oncogenic potential. Cancer Lett 332, 30-34.
Prelle C, Bursen A, Dingermann T, Marschalek R (2013). Secondary mutations in t(4;11) leukemia patients. Leukemia 27, 1425-1427.
Lee SG, Cho SY, Kim MJ, Oh SH, Cho EH, Lee S, Baek EJ, Choi JH, Bohlander SK, Lode L, Richebourg S, Yoon HJ, Marschalek R, Meyer C, Park TS (2012). Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias. Haematologica 98, e55-7.
Yang JJ, Oh SH, Meyer C, Marschalek R, Park TS (2013). RE: Acute myeloid leukemia associated with FGFR1 abnormalities. Int J Hematol 2013 Jun 7. [Epub ahead of print].
Tuborgh A, Meyer C, Marschalek R, Preiss B, Hasle H, Kjeldsen E (2013). Complex Three-Way Translocation Involving MLL , ELL , RREB1 , and CMAHP Genes in an Infant with Acute Myeloid Leukemia and t(6;19;11)(p22.2;p13.1;q23.3). Cytogenet Genome Res 2013 May 30. [Epub ahead of print].
Launay E, Henry C, Meyer C, Chappe C, Taque S, Boulland ML, Abdelali RB, Dugay F, Marschalek R, Bastard C, Fest T, Gandemer V, Belaud-Rotureau MA (2013). MLL-SEPT5 Fusion Transcript in Infant Acute Myeloid Leukemia with t(11;22)(q23;q11). Leuk Lymphoma 2013 Jun 3. [Epub ahead of print].
Meyer C, Zur Stadt U, Escherich G, Hofmann J, Binato R, Barbosa Tda C, Emerenciano M, Pombo-de-Oliveira MS, Horstmann M, Marschalek R (2013). Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients. Am J Blood Res 3, 165-173.
Meyer C, Hofmann J, Burmeister T, Gröger D, Park TS, Emerenciano M, Pombo de Oliveira M, Renneville A, Villarese P, Macintyre E, Cave H, Clappier E, Mass-Malo K, Zuna J, Trka J, De Braekeleer E, De Braekeleer M, Oh SH, Tsaur G, Fechina L, van der Velden VH, van Dongen JJ, Delabesse E, Binato R, Silva ML, Kustanovich A, Aleinikova O, Harris MH, Lund-Aho T, Juvonen V, Heidenreich O, Vormoor J, Choi WW, Jarosova M, Kolenova A, Bueno C, Menendez P, Wehner S, Eckert C, Talmant P, Tondeur S, Lippert E, Launay E, Henry C, Ballerini P, Lapillone H, Callanan MB, Cayuela JM, Herbaux C, Cazzaniga G, Kakadiya PM, Bohlander S, Ahlmann M, Choi JR, Gameiro P, Lee DS, Krauter J, Cornillet-Lefebvre P, Te Kronnie G, Schäfer BW, Kubetzko S, Alonso CN, Zur Stadt U, Sutton R, Venn NC, Izraeli S, Trakhtenbrot L, Madsen HO, Archer P, Hancock J, Cerveira N, Teixeira MR, Lo Nigro L, Möricke A, Stanulla M, Schrappe M, Sedek L, Szczepanski T, Zwaan CM, Coenen EA, van den Heuvel-Eibrink MM, Strehl S, Dworzak M, Panzer-Grümayer R, Dingermann T, Klingebiel T, Marschalek R (2013). The MLL recombinome of acute leukemias in 2013. Leukemia 2013 Apr 30. doi: 10.1038/leu.2013.135. [Epub ahead of print].
Binato R, Meyer C, Macedo-Silva ML, Garcia D, Figueiredo A, Hofmann J, Vieira TP, Abdelhay E, Marschalek R (2013). Analyzing acute leukemia patients with complex MLL rearrangements by a sequential LDI-PCR approach. Cancer Lett 2013 Apr 2. doi:pii: S0304-3835(13)00271-1. 10.1016/j.canlet.2013.03.029. [Epub ahead of print].
Emerenciano M, Meyer C, Mansur MB, Marschalek R, Pombo-de-Oliveira MS; Brazilian Collaborative Study Group of Infant Acute Leukaemia. The distribution of MLL breakpoints correlates with outcome in infant acute leukaemia. Br J Haematol 161, 224-236.
Emerenciano M, Kowarz E, Karl K, de Almeida Lopes B, Scholz B, Bracharz S, Meyer C, Pombo-de-Oliveira MS, Marschalek R (2013). Functional analysis of the two reciprocal fusion genes MLL-NEBL and NEBL-MLL reveal their oncogenic potential. Cancer Lett 332, 30-34.
Prelle C, Bursen A, Dingermann T, Marschalek R (2013). Secondary mutations in t(4;11) leukemia patients. Leukemia 27, 1425-1427.
Lee SG, Cho SY, Kim MJ, Oh SH, Cho EH, Lee S, Baek EJ, Choi JH, Bohlander SK, Lode L, Richebourg S, Yoon HJ, Marschalek R, Meyer C, Park TS (2012). Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias. Haematologica 98, e55-7.
2012
Kim MJ, Yang JJ, Meyer C, Marschalek R, Park TS (2012). Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia. Korean J Hematol 47, 307-308.
Burmeister T, Molkentin M, Meyer C, Lachmann N, Schwartz S, Friedrichs B, Beyer J, Blau IW, Lohm G, Tietze-Bürger C, Marschalek R, Uharek L (2012). Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse. Exp Hematol Oncol 1, 6.
Coenen EA, Driessen EM, Zwaan CM, Stary J, Baruchel A, de Haas V, de Bont ES, Reinhardt D, Kaspers GJ, Arentsen-Peters ST, Meyer C, Marschalek R, Pieters R, Stam RW, van den Heuvel-Eibrink MM (2012). CBL mutations do not frequently occur in paediatric acute myeloid leukaemia. Br J Haematol 159, 577-584.
Türkmen S, Timmermann B, Bartels G, Gröger D, Meyer C, Schwartz S, Haferlach C, Rieder H, Gökbuget N, Hoelzer D, Marschalek R, Burmeister T (2012). Involvement of the MLL gene in adult T-lymphoblastic leukemia. Genes Chrom Cancer 51, 1114-1124.
Lee SG, Park TS, Yang JJ, Oh SH, Cho EH, Lee S, Oh D, Huh JY, Marschalek R, Meyer C (2012). Molecular identification of a new splicing variant of the MLL - MLLT11 fusion transcript in an adult with acute myeloid leukemia and t(1;11)(q21;q23). Acta Haematol 128, 131-138.
Cerveira N, Lisboa S, Correia C, Bizarro S, Santos J, Torres L, Vieira J, Barros-Silva JD, Pereira D, Moreira C, Meyer C, Oliva T, Moreira I, Martins A, Viterbo L, Costa V, Marschalek R, Pinto A, Mariz JM, Teixeira MR (2012). Genetic and clinical characterization of 45 acute leukemia patients with MLL gene rearrangements from a single institution. Mol Oncol 6, 553-564.
Yang JJ, Marschalek R, Meyer C, Park TS (2012). Diagnostic usefulness of genomic breakpoint analysis of various gene rearrangements in acute leukemias: a perspective of long distance- or long distance inverse-PCR-based approaches. Ann Lab Med 32, 316-318.
Scholz B, Marschalek R (2012). Epigenetics and blood disorders. Br J Haematol 158, 307-322.
Ussowicz M, Jaskowiec A, Meyer C, Marschalek R, Chybicka A, Szczepanski T, Haus O (2012). A three-way translocation of MLL, MLLT11, and the novel reciprocal partner gene MYO18A in a child with acute myeloid leukemia. Cancer Genet 205, 261-265.
Park TS, Jeon YL, Lee HJ, Jeong JH, Kim SY, Cho EH, Marschalek R, Meyer C (2012). Detection of EML4-ALK and other ALK fusion genes in lung cancer: a lesson from the leukemia fusion gene analysis and future application. J Korean Med Sci 27, 576-577.
Yang JJ, Park TS, Kim MJ, Cho EH, Oh SH, Jeon BR, Oh D, Huh JY, Marschalek R, Meyer C. Acute promyelocytic leukemia with trisomy 8 showing normal PML-RARA FISH signal patterns: diagnostic application of long-distance polymerase chain reaction in molecularly discrepant leukemia cases. Ann Hematol 91, 1645-1648.
Coenen EA, Zwaan CM, Meyer C, Marschalek R, Creutzig U, Pieters R, Bradtke J, van den Heuvel-Eibrink MM (2012). Abl-interactor 2 (ABI2): A novel MLL translocation partner in acute myeloid leukemia. Leuk Res 36, e113-5.
Yang JJ, Park TS, Choi JR, Park SJ, Cho SY, Jun KR, Kim HR, Lee JN, Oh SH, Lee S, Kim B, Marschalek R, Meyer C (2012). Submicroscopic Deletion of FGFR1 Gene Is Recurrently Detected in Myeloid and Lymphoid Neoplasms Associated with ZMYM2-FGFR1 Rearrangements: A Case Study. Acta Haematol 127, 119-123.
de Braekeleer E, Douet-Guilbert N, Meyer C, van Deventer FM, Marschalek R, de Braekeleer M (2012). MLL-ELL fusion gene in two infants with acute monoblastic leukemia and myeloid sarcoma. Leuk Lymphoma 53, 1222-1224.
Cho SY, Park TS, Oh SH, Cho EH, Oh D, Huh JY, Marschalek R, Meyer C (2012). Genomic analysis of a four-way t(4;11;22;10) associated with MLL-AF4 in an adult acute lymphoblastic leukemia. Ann Hematol 91, 977-979.
Herbaux C, Poulain S, Meyer C, Marschalek R, Renneville A, Fernandes J, Theisen O, Tricot S, Simon M, Duthilleul P, Daudignon A (2012). TOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia. Br J Haematol. 157, 128-131.
Burmeister T, Molkentin M, Meyer C, Lachmann N, Schwartz S, Friedrichs B, Beyer J, Blau IW, Lohm G, Tietze-Bürger C, Marschalek R, Uharek L (2012). Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse. Exp Hematol Oncol 1, 6.
Coenen EA, Driessen EM, Zwaan CM, Stary J, Baruchel A, de Haas V, de Bont ES, Reinhardt D, Kaspers GJ, Arentsen-Peters ST, Meyer C, Marschalek R, Pieters R, Stam RW, van den Heuvel-Eibrink MM (2012). CBL mutations do not frequently occur in paediatric acute myeloid leukaemia. Br J Haematol 159, 577-584.
Türkmen S, Timmermann B, Bartels G, Gröger D, Meyer C, Schwartz S, Haferlach C, Rieder H, Gökbuget N, Hoelzer D, Marschalek R, Burmeister T (2012). Involvement of the MLL gene in adult T-lymphoblastic leukemia. Genes Chrom Cancer 51, 1114-1124.
Lee SG, Park TS, Yang JJ, Oh SH, Cho EH, Lee S, Oh D, Huh JY, Marschalek R, Meyer C (2012). Molecular identification of a new splicing variant of the MLL - MLLT11 fusion transcript in an adult with acute myeloid leukemia and t(1;11)(q21;q23). Acta Haematol 128, 131-138.
Cerveira N, Lisboa S, Correia C, Bizarro S, Santos J, Torres L, Vieira J, Barros-Silva JD, Pereira D, Moreira C, Meyer C, Oliva T, Moreira I, Martins A, Viterbo L, Costa V, Marschalek R, Pinto A, Mariz JM, Teixeira MR (2012). Genetic and clinical characterization of 45 acute leukemia patients with MLL gene rearrangements from a single institution. Mol Oncol 6, 553-564.
Yang JJ, Marschalek R, Meyer C, Park TS (2012). Diagnostic usefulness of genomic breakpoint analysis of various gene rearrangements in acute leukemias: a perspective of long distance- or long distance inverse-PCR-based approaches. Ann Lab Med 32, 316-318.
Scholz B, Marschalek R (2012). Epigenetics and blood disorders. Br J Haematol 158, 307-322.
Ussowicz M, Jaskowiec A, Meyer C, Marschalek R, Chybicka A, Szczepanski T, Haus O (2012). A three-way translocation of MLL, MLLT11, and the novel reciprocal partner gene MYO18A in a child with acute myeloid leukemia. Cancer Genet 205, 261-265.
Park TS, Jeon YL, Lee HJ, Jeong JH, Kim SY, Cho EH, Marschalek R, Meyer C (2012). Detection of EML4-ALK and other ALK fusion genes in lung cancer: a lesson from the leukemia fusion gene analysis and future application. J Korean Med Sci 27, 576-577.
Yang JJ, Park TS, Kim MJ, Cho EH, Oh SH, Jeon BR, Oh D, Huh JY, Marschalek R, Meyer C. Acute promyelocytic leukemia with trisomy 8 showing normal PML-RARA FISH signal patterns: diagnostic application of long-distance polymerase chain reaction in molecularly discrepant leukemia cases. Ann Hematol 91, 1645-1648.
Coenen EA, Zwaan CM, Meyer C, Marschalek R, Creutzig U, Pieters R, Bradtke J, van den Heuvel-Eibrink MM (2012). Abl-interactor 2 (ABI2): A novel MLL translocation partner in acute myeloid leukemia. Leuk Res 36, e113-5.
Yang JJ, Park TS, Choi JR, Park SJ, Cho SY, Jun KR, Kim HR, Lee JN, Oh SH, Lee S, Kim B, Marschalek R, Meyer C (2012). Submicroscopic Deletion of FGFR1 Gene Is Recurrently Detected in Myeloid and Lymphoid Neoplasms Associated with ZMYM2-FGFR1 Rearrangements: A Case Study. Acta Haematol 127, 119-123.
de Braekeleer E, Douet-Guilbert N, Meyer C, van Deventer FM, Marschalek R, de Braekeleer M (2012). MLL-ELL fusion gene in two infants with acute monoblastic leukemia and myeloid sarcoma. Leuk Lymphoma 53, 1222-1224.
Cho SY, Park TS, Oh SH, Cho EH, Oh D, Huh JY, Marschalek R, Meyer C (2012). Genomic analysis of a four-way t(4;11;22;10) associated with MLL-AF4 in an adult acute lymphoblastic leukemia. Ann Hematol 91, 977-979.
Herbaux C, Poulain S, Meyer C, Marschalek R, Renneville A, Fernandes J, Theisen O, Tricot S, Simon M, Duthilleul P, Daudignon A (2012). TOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia. Br J Haematol. 157, 128-131.
2011
Meyer C, Kowarz E, Yip SF, Wan TS, Chan TK, Dingermann T, Chan LC, Marschalek R (2011). A complex MLL rearrangement identified five years after initial MDS diagnosis results in out-of-frame fusions without progression to acute leukemia. Cancer Genet 204, 557-562.
De Braekeleer E, Meyer C, Douet-Guilbert N, Basinko A, Le Bris MJ, Morel F, Berthou C, Marschalek R, Ferec C, De Braekeleer M (2011). Identification of MLL partner genes in 27 patients with acute leukemia from a single cytogenetic laboratory. Mol Oncol 5, 555-563.
Lee SG, Park TS, Oh SH, Park JC, Yang YJ, Marschalek R, Meyer C, Cho EH, Shin SY (2011). De novo Acute Myeloid Leukemia Associated with t(11;17)(q23;q25) and MLL-SEPT9 Rearrangement in an Elderly Patient: A Case Study and Review of the Literature. Acta Haematol 126, 195-198.
Lim G, Cho EH, Cho SY, Shin SY, Park JC, Yang YJ, Oh SH, Marschalek R, Meyer C, Park TS (2011). A novel PML-ADAMTS17-RARA gene rearrangement in a patient with pregnancy-related acute promyelocytic leukemia. Leuk Res 35, e106-110.
Emerenciano M, Meyer C, Macedo-Silva ML, de Meis E, Dobbin JA, Marschalek R, Pombo-de-Oliveira MS (2011). Backtracking to birth of the NUP98-HOXD13 gene fusion in an infant acute myeloid leukemia. Leukemia 25, 1192-1194.
Cin H, Meyer C, Herr R, Janzarik WG, Lambert S, Jones DT, Jacob K, Benner A, Witt H, Remke M, Bender S, Falkenstein F, Van Anh TN, Olbrich H, von Deimling A, Pekrun A, Kulozik AE, Gnekow A, Scheurlen W, Witt O, Omran H, Jabado N, Collins VP, Brummer T, Marschalek R, Lichter P, Korshunov A, Pfister SM (2011). Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma. Acta Neuropathol 121, 763-774.
Kuster L, Kaindl U, Fuka G, Krapf G, Inthal A, Mann G, Kauer M, Rainer J, Kofler R, Hall A, Metzler M, Meyer C, Harbott J, Marschalek R, Strehl S, Haas OA, Panzer-Grümayer R (2011). ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling. Blood 117, 2658-2667.
Zaliova M, Meyer C, Cario G, Marschalek R, Stary J, Zuna J, Trka R (2011). TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases. Pediatric Blood Cancer 56, 217-225.
Bielorai B, Meyer C, Trakhtenbrot L, Golan H, Rozner E, Amariglio N, Izraeli S, Marschalek R, Toren A (2011). Therapy-related acute myeloid leukemia with t(2;11)(q37;q23) after treatment for osteosarcoma. Cancer Genet Cytogenet 203, 288-291.
Kim MJ, Cho SY, Kim MH, Lee JJ, Kang SY, Cho EH, Huh J, Yoon HJ, Park TS, Lee WI, Marschalek R, Meyer C (2011). FISH-negative cryptic PML-RARA rearrangement detected by long-distance polymerase chain reaction and sequencing analyses: a case study and review of the literature. Cancer Genet Cytogenet 203, 278-283.
Marschalek R (2011). Mechanisms of leukemogenesis by MLL fusion proteins. Br J Haematol 152, 141-154.
Kuipers JE, Coenen EA, Balgobind BV, Stary J, Baruchel A, de Haas V, de Bont ES, Reinhardt D, Kaspers GJ, Cloos J, Danen-van Oorschot AA, den Boer ML, Marschalek R, Meyer C, Pieters R, Zwaan CM, van den Heuvel-Eibrink MM (2011). High IGSF4 expression in pediatric AML M5 with t(9;11). Blood 117, 928-935.
Balgobind BV, van den Heuvel-Eibrink MM, Menezes RX, Reinhardt D, Hollink IHIM, Peters STJCM, van Wering ER, Kaspers GJL, Cloos J, de Bont ESJM, Cayuela JM, Baruchel A, Meyer C, Marschalek R, Trka J, Stary J, Beverloo HB, Pieters R, Zwaan CM, den Boer ML (2011). Evaluation of gene expression signatures predictive for cytogenetic and molecular subtypes of pediatric acute myeloid leukemia. Haematologica 96, 221-230.
Coenen EA, Zwaan CM, Meyer C, Marschalek R, Pieters R, Beverloo HB and van den Heuvel-Eibrink MM (2010). KIAA1524: a novel MLL translocation partner in AML. Leuk Res 35, 133-115.
2010
Cerveira N, Meyer C Santos J, Torres L, Lisboa S, Pinheiro M, Bizarro S, Correia C, Norton L, Marschalek R, Teixeira MR (2010). A Novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia. BMC Cancer 10, 518.
Balgobind BV, Zwaan CM, Reinhardt D, Arentsen-Peters TJCM, Hollink IHIM, de Haas V, Kaspers GJL, de Bont ESJM, Baruchel A, Stary J, Meyer C, Marschalek R, Creutzig U, Pieters R, Van den Heuvel-Eibrink MM (2010) High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome. Leukemia 24, 2048-2055.
Alonso CN, Gallego MS, Rossi JG, Mansini AP, Rubio PL, Meyer C, Marschalek R, Felice MS (2010). BTBD18: a novel MLL partner gene in an infant with acute lymphoblastic leukemia and inv(11)(q13;q23). Leuk Res 34, e294-296.
Zuna J, Zaliova M, Muzikova K, Meyer C, Lizcova L, Zemanova Z, Votava F, Marschalek R, Stary J, Trka J (2010). Acute leukaemias with TEL/ABL fusion define a novel subgroup with poor prognosis and prenatal origin. Genes Chrom Cancer 9, 873-884.
De Braekeleer E, Meyer C, Le Bris MJ, Douet-Guilbert N, Basinko A, Morel F, Berthou C, Marschalek R, Ferec C, De Braekeleer M (2010). Identification of an MLL-MLLT4 fusion gene resulting from a t(6;11)(q27;q23) presenting as a del(11q) in a child with T-cell acute lymphoblastic leukemia. Leuk Lymphoma 51, 1570-1573.
Hutter C, Attarbaschi, Fischer S, Meyer C, Dworzak M, König M, Marschalek R, Mann G, Haas OA, Panzer-Grümayer ER (2010). Acute monocytic leukaemia originating from MLL-MLLT3-positive pre-B cells. Br J Haematol 150, 621-623.
Coser V, Meyer C, Basegio R, Menezes J, Marschalek R, Pombo-de-Oliveira MS (2010). Nebulette is the second member of the Nebulin family fused to the MLL gene in infant leukemia. Cancer Genet Cytogenet 198, 151-154.
Marschalek R (2010). Mixed lineage leukemias: roles in human malignancies and potential therapy. FEBS J 277:1822-1831.
De Braekeleer E, Meyer C, Douet-Guilbert N, Morel F, Le Bris MJ, Berthou C, Arnaud B, Marschalek R, Ferec C, De Braekeleer M (2010). Complex and cryptic chromosomal rearrangements involving the MLL gene in acute leukemia: a study of 7 patients. Blood Cell Mol Disease 44, 268-274.
Lee SG, Park TS, Wonc SC, Song J, Lee KA, Choi JR, Marschalek R, Meyer C (2010). Three-way translocation involving MLL, MLLT1, and new third partner, NRXN1 in a patient with acute lymphoblastic leukemia with t(2;19;11)(p12;p13.3;q23). Cancer Genet Cytogenet 197, 32-38.
2009
Röhrs S, Dirks WG, Meyer C, Marschalek R, Scherr M, Slany R, Wallace A, Drexler HG, Quentmeier H (2009). Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in Acute Myeloid Leukemia. Mol Cancer 8, 86.
Park TS, Lee S-G, Song J, Lee K-A, Kim J, Choi TL, Marschalek R, Meyer C (2009). CASP8AP2: A novel partner gene of MLL rearrangement with t(6;11)(q15;23) in acute myeloid leukemia. Cancer Genet Cytogenet 195, 94-95.
De Braekeleer E, Douet-Guilbert N, Morel F, Le Bris MJ, Meyer C, Marschalek R, Férec C, De Braekeleer M (2009). FLNA, a new partner gene fused to MLL in a patient with acute myelomonoblastic leukemia. Br J Haematol 146, 693-695.
Trentin L, Girodan M, Dingermann T, Basso G, te Kronnie G, Marschalek R (2009). Two independent gene signatures in pediatric t(4;11) acute lymphoblastic leukemia patients. Eur J Haematol 83, 406-419.
Balgobind BV, Zwaan CM, Meyer C, Marschalek R, van Galen JF, van Drunen E, Pieters R, Beverloo HB, van den Heuvel-Eibrink M (2009). NRIP3: A novel translocation partner of MLL detected in a pediatric AML with complex chromosome 11 rearrangements. Haematologica 94, 1033.
Krauter J, Wagner K, Schäfer I, Marschalek R, Meyer C, Heil G, Schaich M, Ehninger G, Niederwieser D, Krahl R, Büchner T, Sauerland C, Schlegelberger B, Döhner K, Döhner H, Schlenk R, Ganser A (2009). Prognostic factors in adult patients up to 60 years with AML and translocations of chromosome band 11q23: Individual patient data based meta-analysis of the German AML-Intergroup. J Clin Oncology 27, 3000-3006.
Derwich K, Sedek L, Meyer C, Pieczonka A, Dawidowska M, Gaworczyk A, Wachowiak J, Konatkowska B, Witt M, Marschalek R, Szczepanski T (2009). Infant acute bilineal leukemia. Leuk Res 33, 1005-1008.
Meyer C and Marschalek R (2009). LDI-PCR: Identification of known and unknown gene fusions ofthe human MLL gene (book chapter). Methods Mol Biol 538: 71-83.
Meyer C, Kowarz E, Hofmann J, Renneville A, Zuna J, Trka J, Ben Abdelali R, Macintyre E, De Braekeleer E, De Braekeleer M, Delabesse E, Pombo de Oliveira M, Cavé H, Clappier E, van Dongen JJM, Balgobind BV, van den Heuvel-Eibrink MM, Beverloo HB, Panzer-Grümayer R, Teigler-Schlegel A, Harbott J, Kjeldsen E, Schnittger S, Koehl U, Gruhn B, Heidenreich O, Chan LC, Yip SF, Krzywinski M, Eckert C, Möricke A, Schrappe M, Alonso CN, Schäfer BW, Krauter J, Lee DA, zur Stadt U, Te Kronnie G, Sutton R, Izraeli S, Trakhtenbrot L, Lo Nigro L, Tsaur G, Fechina L, Szczepanski T, Strehl S, Ilencikova D, Molkentin M, Burmeister T, Dingermann T, Klingebiel T, Marschalek R (2009). New insights into the MLL recombinome of acute leukemias. Leukemia 23, 1490-1499.
De Braekeleer E, Lanotto JC, Douet-Guilbert N, Meyer C, Le Bris MJ, Marschalek R, Berthou C, Férec C, De Braekeleer M (2009). A second case of secondary acute myeloblastic leukemia associated with the MLL-KIAA0284 fusion gene. Blood Cells Mol Dis 42, 292-293.
Van der Velden VH, Corral L, Valsecchi MG, Jansen MW, De Lorenzo P, Cazzaniga G, Panzer-Grümayer ER, Schrappe M, Schrauder A, Meyer C, Marschalek R, Nigro LL, Metzler M, Basso G, Mann G, Den Boer ML, Biondi A, Pieters R, Van Dongen JJ (2009). Prognostic significance of minimal residual disease in infants with acute lymphoblastic leukemia treated within the Interfant-99 protocol. Leukemia 23,1073-1079.
Meyer C, Brieger A, Plotz G, Weber N, Passmann S, Dingermann T, Zeuzem S, Trojan J, Marschalek R (2009). An Interstitial Deletion at 3p21.3 Results in the Genetic Fusion of MLH1 and ITGA9 in a Lynch Syndrome Family. Clin Cancer Res 15, 762-769.
Burmeister T, Meyer C, Schwartz S, Hofmann J, Molkentin M, Hubert D, Schneider B, Raff T, Reinhardt R, Gökbuget N, Hoelzer D, Thiel E, Marschalek R (2009). The MLL recombinome of adult acute lymphoblastic leukemia – results from the GMALL study group. Blood 113, 4011-4015.
De Braekeleer E, Meyer C, Douet-Guilbert N, Morel F, Le Bris M-J, Marschalek R, Férec C, De Braekeleer M (2009). A complex 1;19;11 translocation involving the MLL gene in a patient with congenital acute monoblastic leukemia identified by molecular and cytogenetic techniques. Ann Hematol 88, 795-797.
Zuna J, Burjanivova T, Mejstrikova E, Zemanova Z, Muzikova K, Meyer C, Horsley SW, Kearney K, Colman S, Ptozskova H, Marschalek R, Hrusak O, Stary J, Greaves M, Trka J (2009). Covert pre-leukaemia driven by MLL gene fusion. Gene Chrom Cancer 48, 98-107.
2008
Marschalek R (2008). Etoposide-treatment and MLL rearrangements. Eur J Haematol 81, 481-482.
Burmeister T, Meyer C, Thiel G, Reinhardt R, Thiel E, Marschalek R (2008). A MLL-KIAA0284 fusion gene in a patient with secondary acute myeloid leukemia and t(11;14)(q23;q32). Blood Cells Mol Dis 41, 210-214.
Soler G, Radford I, Meyer C, Marschalek R, Brouzes C, Ghez D, Romana S, Berger R (2008). MLL insertion with MLL-MLLT3 gene fusion in acute leukemia: case report and review of the literature. Cancer Genet Cytogenet 183, 53-59.
Metzler M, Staege MS, Harder L, Mendelova D, Zuna J, Frankova E, Meyer C, Flohr T, Bednarova D, Harbott J, Langer T, Gesk S, Trka J, Siebert R, Marschalek R, Niemeyer C, Rascher W (2008). Inv(11)(q21q23) Fuses MLL to the NOTCH Co-Activator Mastermind-Like 2 in Secondary T-Cell Acute Lymphoblastic Leukemia. Leukemia 22, 1807-1811.
Burmeister T, Meyer C, Thiel G, Reinhardt R, Thiel E, Marschalek R (2008). A MLL-KIAA0284 fusion gene in a patient with secondary acute myeloid leukemia and t(11;14)(q23;q32). Blood Cells Mol Dis 41, 210-214.
Soler G, Radford I, Meyer C, Marschalek R, Brouzes C, Ghez D, Romana S, Berger R (2008). MLL insertion with MLL-MLLT3 gene fusion in acute leukemia: case report and review of the literature. Cancer Genet Cytogenet 183, 53-59.
Metzler M, Staege MS, Harder L, Mendelova D, Zuna J, Frankova E, Meyer C, Flohr T, Bednarova D, Harbott J, Langer T, Gesk S, Trka J, Siebert R, Marschalek R, Niemeyer C, Rascher W (2008). Inv(11)(q21q23) Fuses MLL to the NOTCH Co-Activator Mastermind-Like 2 in Secondary T-Cell Acute Lymphoblastic Leukemia. Leukemia 22, 1807-1811.
2007
Choi WT, Folsom MR, Azim MF, Meyer C, Kowarz E, Rolf Marschalek R, Timchenko NA, Naeem RC, Lee DA (2007). CEBP-beta suppression by interuption of CUGBP1 resulting from a complex rearrangement of MLL. Cancer Genet Cytogenet 177, 108-114.
Zuna J, Cavé H, Eckert E, Szczepanski T, Meyer C, Mejstrikova E, Fronkova E, Muzikova K, Clappier E, Mendelova D, Boutard P, Schrauder A, Sterba J, Marschalek R, van Dongen JJM, Hrusak O, Stary J, Jan Trka J (2007). Childhood Secondary ALL after ALL Treatment. Leukemia 21:1431-1435.
Kowarz E, Burmeister T, Nigro LL, Jansen MWJC, Delabesse E, Klingebiel T, Dingermann T, Meyer C, Marschalek R (2007). Complex MLL rearrangements in MLL•AF4+/AF4•MLL- leukemia patients conceal the presence of reciprocal MLL fusion genes. Leukemia 21, 1232-1238.
Jansen MWJC, Corral L, van der Velden VHJ, Panzer-Grümayer R, Schrappe M, Schrauder A, Marschalek R, Meyer C, den Boer ML, Hop WJC, Basso G, Biondi A, Pieters R, van Dongen JJM (2007). Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement. Leukemia 21, 633-641.
Meyer C, Burmeister T, Strehl, Zach O, Schneider B, Haas OA, Klingebiel T, Dingermann T, Marschalek R (2007). Spliced MLL fusions: a novel mechanism to generate functional chimaeric MLL•MLLT1 transcripts in t(11;19)(q23;p13.3) leukaemia. Leukemia 21, 588-590.
Zuna J, Cavé H, Eckert E, Szczepanski T, Meyer C, Mejstrikova E, Fronkova E, Muzikova K, Clappier E, Mendelova D, Boutard P, Schrauder A, Sterba J, Marschalek R, van Dongen JJM, Hrusak O, Stary J, Jan Trka J (2007). Childhood Secondary ALL after ALL Treatment. Leukemia 21:1431-1435.
Kowarz E, Burmeister T, Nigro LL, Jansen MWJC, Delabesse E, Klingebiel T, Dingermann T, Meyer C, Marschalek R (2007). Complex MLL rearrangements in MLL•AF4+/AF4•MLL- leukemia patients conceal the presence of reciprocal MLL fusion genes. Leukemia 21, 1232-1238.
Jansen MWJC, Corral L, van der Velden VHJ, Panzer-Grümayer R, Schrappe M, Schrauder A, Marschalek R, Meyer C, den Boer ML, Hop WJC, Basso G, Biondi A, Pieters R, van Dongen JJM (2007). Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement. Leukemia 21, 633-641.
Meyer C, Burmeister T, Strehl, Zach O, Schneider B, Haas OA, Klingebiel T, Dingermann T, Marschalek R (2007). Spliced MLL fusions: a novel mechanism to generate functional chimaeric MLL•MLLT1 transcripts in t(11;19)(q23;p13.3) leukaemia. Leukemia 21, 588-590.
2006
Strehl S, Koenig M, Meyer C, Schneider B, Harbott J, Jäger U, von Bergh A, Loncarevic I, Jarosova M, Schmidt H, Moore SDP, Marschalek R, Haas OA (2006). Molecular dissection of t(11;17) in acute myeloid leukemia reveals a variety of gene fusions with heterogeneous fusion transcripts and multiple splice variants. Genes Chrom Cancer 45, 1041-11049.
Meyer C, Kowarz E, Schneider B, Oehm C, Klingebiel T, Dingermann T, Marschalek R (2006). Genomic DNA of leukemia patients: target for clinical diagnosis of MLL rearrangements. Biotechnol J 1, 656-663.
Attarbaschi A, Mann G, König M, Steiner M, Strehl S, Schneider B, Schreiberhuber A, Borkhardt A, Marschalek R, Pickl W, Lion T, Gadner H, Haas OA, Dworzak M; on behalf of the Austrian Berlin-Frankfurt-Münster (BFM) Cooperative Study Group (2006). MLL-involving translocations predominantly occur in CD10–/CDw65+/CD15+ childhood pro-B and pre-B acute lymphoblastic leukaemia (ALL). Clin Cancer Res 12, 2988-2994.
Burjanivova T, Madzo J, Muzikova K, Meyer C, Schneider B, Votava F, Marschalek R, Stary J, Trka J, Zuna J (2006). Prenatal origin of childhood AML occurs less frequently than in childhood ALL. BMC Cancer 6, 100
Meyer C, Schneider B, Jakob S, Strehl S, Schnittger S, Schoch C, Jansen MWJC, van Dongen JJM, den Boer ML, Pieters R, Ennas MG, Angelucci E, Koehl U, Greil J, Griesinger F, zur Stadt U, Eckert C, Szczepanski T, Niggli FK, Schäfer BW, Kempski H, Brady HJM, Trka J, Lo Nigro L, Biondi A, Delabesse E, Macintyre E, Stanulla M, Schrappe M, Haas OA, Burmeister T, Dingermann T, Klingebiel T, Marschalek R (2006). The MLL recombinome of acute leukemias. Leukemia 20, 777-784.
Burmeister T, Marschalek R, Schneider B, Meyer C, Gökbuget N, Schwartz S, Hoelzer D, Thiel E (2006). Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations. Leukemia 20, 451-457.
Meyer C, Kowarz E, Schneider B, Oehm C, Klingebiel T, Dingermann T, Marschalek R (2006). Genomic DNA of leukemia patients: target for clinical diagnosis of MLL rearrangements. Biotechnol J 1, 656-663.
Attarbaschi A, Mann G, König M, Steiner M, Strehl S, Schneider B, Schreiberhuber A, Borkhardt A, Marschalek R, Pickl W, Lion T, Gadner H, Haas OA, Dworzak M; on behalf of the Austrian Berlin-Frankfurt-Münster (BFM) Cooperative Study Group (2006). MLL-involving translocations predominantly occur in CD10–/CDw65+/CD15+ childhood pro-B and pre-B acute lymphoblastic leukaemia (ALL). Clin Cancer Res 12, 2988-2994.
Burjanivova T, Madzo J, Muzikova K, Meyer C, Schneider B, Votava F, Marschalek R, Stary J, Trka J, Zuna J (2006). Prenatal origin of childhood AML occurs less frequently than in childhood ALL. BMC Cancer 6, 100
Meyer C, Schneider B, Jakob S, Strehl S, Schnittger S, Schoch C, Jansen MWJC, van Dongen JJM, den Boer ML, Pieters R, Ennas MG, Angelucci E, Koehl U, Greil J, Griesinger F, zur Stadt U, Eckert C, Szczepanski T, Niggli FK, Schäfer BW, Kempski H, Brady HJM, Trka J, Lo Nigro L, Biondi A, Delabesse E, Macintyre E, Stanulla M, Schrappe M, Haas OA, Burmeister T, Dingermann T, Klingebiel T, Marschalek R (2006). The MLL recombinome of acute leukemias. Leukemia 20, 777-784.
Burmeister T, Marschalek R, Schneider B, Meyer C, Gökbuget N, Schwartz S, Hoelzer D, Thiel E (2006). Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations. Leukemia 20, 451-457.
2005
Teuffel O, Betts DR, Thali M, Eberle D, Meyer C, Schneider B, Marschalek R, Trakhtenbrot L, Amariglio N, Niggli FK, Schäfer BW (2005). Clonal expansion of a new MLL rearrangement in the absence of leukemia. Blood 105, 4151-4152.
Meyer C, Schneider B, Reichel M, Angermüller S, Strehl S, Schnittger S, Schoch C, Jansen, MJC, van Dongen JJ, Pieters R, Haas OA, Dingermann T, Klingebiel T, Marschalek R (2005). A new diagnostic tool for the identification of MLL rearrangements including unknown partner genes. Proc Natl Acad Sci USA 102, 449-454.
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