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Group Frank Schnütgen

Publications

Frank Schnütgen
 2011

Elling, U., Taubenschmid, J., Wirnsberger, G., O'Malley, R., Demers, S.-P., Vanhaelen, Q., Shukalyuk, A.I., Schmauss, G., Schramek, D., Schnütgen, F., von Melchner, H., Ecker, J.R., Stanford, W.L., Zuber, J., Stark, A., and Penninger, J.M.
Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells.
Cell Stem Cell, 9, 563-547 (2011)

Schnütgen, F., Ehrmann, F., Poser, I., Hubner, N.C., Hansen, J., Floss, T., deVries, I., Wurst, W., Hyman, A., Mann, M., and von Melchner, H.
Resources for proteomics in mouse embryonic stem cells.
Nature Meth. 8, 103-104 (2011)

Schnütgen, F., Ehrmann, F., Ruiz-Noppeinger, P., and von Melchner, H.
High throughput gene trapping and postinsertional modifications of gene trap alleles.
in Extracting function from the mammalian genome, Methods Journal (ed. H. von Melchner, A.F. Stewart), Elsvier/Academic Press, pp. in press (2011)

 2010

Schebelle, L., Wolf, C., Stribl, C., Javaheri, T., Schnütgen, F., Ettinger, A., Ivics, Z., Hansen, J., Ruiz, P., von Melchner, H., Wurst, W., and Floss, T.
Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps.
Nucl. Acids Res. 38, e106 (2010)

 2009

De-Zolt, S., Altschmied, J., Ruiz, P., von Melchner, H., and Schnütgen, F.
Gene-trap vectors and mutagenesis.
Meth. Mol. Biol. 530, 29-47, (2009)

 2008

Schnütgen, F., Hansen, J., De-Zolt, S., Horn, C., Lutz, M., Floss, T., Wurst, W., Noppinger, P. R., and von Melchner, H.
Enhanced gene trapping in mouse embryonic stem cells.
Nucl. Acids Res. 36, e133, (2008)

Floss, T., and Schnütgen, F.
Conditional gene trapping using the FlEx system
Meth. Mol. Biol. 435, 127-138, (2008)

 2007

Horn, C., Hansen, J., Schnütgen, F., Seisenberger, C., Floss, T., Irgang, M., De-Zolt, S., Wurst, W., von Melchner, H., and Ruiz, P.
Splinkerette PCR for more efficient characterization of gene trap events.
Nature Genetics 8, 933-943, (2007)

Wegmeyer, H., Egea, J., Rabe, N., Gezelius, H., Filosa, A., Enjin, A., Varoqueaux, F., Deininger, K., Schnütgen, F., Brose, N., Klein, R., Kullander, K., and Betz, A.
EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin.
Neuron 55, 756-767, (2007)

Schnütgen, F., and Gyselinck, N.B.
Adopting the good reFLEXes to generate conditional alterations in the mouse genome.
Transgenic Research 16, 405, (2007)

 2006

Schnütgen, F. , Stewart, A. F., von Melchner, H., and Anastassiadis, K.
Engineering ES cells with recombinase systems.
Meth. Enzymol. 420, 100-136, (2006)

De-Zolt, S., Schnütgen, F., Seisenberger, C., Hansen, J., Hollatz, M., Floss, T., Ruiz, P., Wurst, W., and von Melchner, H.
High throughput trapping of secretory pathway genes in mouse embryonic stem cells.
Nucl. Acids Res. 34, e25, (2006)

Schnütgen, F.
Generation of multipurpose alleles for the functional analysis of the mouse genome.
Brief. Funct. Genomic. Proteomic. 5, 15-18, (2006)

 2005

Schnütgen, F. , De-Zolt, S., Van Sloun, P., Hollatz, M., Floss, T., Hansen, J., Altschmied, J., Seisenberger, C., Ghyselinck, N. B., Ruiz, P., Chambon, P., Wurst, W., and von Melchner, H.
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome.
Proc. Acad. Natl. Sci. USA 102, 7221-7226, (2005)

 2003

Hansen, J., Floss, T., Van Sloun, P., Füchtbauer, E.-M., Vauti, F., Arnold, H. H., Schnütgen, F., Wurst, W., von Melchner, H., and Ruiz, P.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Proc. Natl. Acad. Sci. U S A 100, 9918-9922, (2003)

Schnütgen, F., Doerflinger, N., Calleja, C., Wendling, O., Chambon, P., and Ghyselinck, N. B.
A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse.
Nat. Biotechnol. 21, 562-565, (2003)

 2002

Floss, T., Wurst, W., von Melchner, H., Van Sloun, P., Schnütgen, F., Füchtbauer, E.-M., Arnold, H.-H., Vauti, F., Ruiz, P. and Hansen, J.
Gene in der Falle: Mutagenese des Mausgenoms.
Biospektrum 8, 84-90, (2002)

 2000

Balendrian, G.,K., Schnütgen, F., Scapin, G., Börchers, T, Xhong, N., Lim, N., Godbout, R., Spener, F., and Sacchettini, J. C.
Crystal structure and thermodynamic analysis of human brain fatty acid binding protein.
J. Biol. Chem. 275, 27045-27054, (2000)

 1997

Schnütgen, F.
Klonierung, Isolierung, Bindungs- und Strukturanalyse des Gehirn-Typ-Fettsäurebindungsproteins.
Dissertation (1997)

 1996

Myers-Payne, S. C., Hubbell, T., Pu, L., Schnütgen, F., Börchers, T., Wood, W. G., Spener, F., and Schroeder, F.
Isolation and characterization of two fatty acid binding proteins from mouse brain.
J. Neurochem 66, 1648-1656, (1996)

Schnütgen, F., Börchers, T., Müller, T., and Spener, F.
Heterologous expression and characterization of mouse brain fatty acid binding protein.
Biol. Chem. Hoppe-Seyler 377, 211-215, (1996)

 1994

Kurtz, A., Zimmer, A., Schnütgen, F., Brüning, G., Spener, and Müller, T.
The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development.
Development 120, 2637-2649, (1994)

immunofluorescence images

Immunofluorescence images

Immunofluorescence images to determine the subcellular localization of nLAP tagged FKBP5 and Ctnnd1.