Schnütgen, F., Ehrmann, F., Ruiz-Noppinger, P., and von Melchner, H.
High throughput gene trapping and postinsertional modifications of gene trap alleles.
Methods, 53, 347-355 (2011)
von Melchner, H., Stewart, A.F.
Methods for extracting function from the mammalian genome.
Methods, 53, 329-330 (2011)
Schnütgen, F., Ehrmann, F., Poser, I., Hubner, N.C., Hansen, J., Floss, T., deVries, I., Wurst, W., Hyman, A., Mann, M., and von Melchner, H.
Resources for proteomics in mouse embryonic stem cells.
Nature Meth. 8, 103-104 (2011)
Schebelle, L., Wolf, C., Stribl, C., Javaheri, T., Schnütgen, F., Ettinger, A., Ivics, Z., Hansen, J., Ruiz, P., von Melchner, H., Wurst, W., and Floss, T.
Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps.
Nucl. Acids Res. 38, e106 (2010)
Wempe, F., De-Zolt, S., Koli, K., Bangsow, T., Parajuli, N., Dumitrascu, R., Sterner-Kock, A., Weissmann, N., Keski-Oja, J., and von Melchner, H.
Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD.
Dis. Model Mech. 3, 246-253 (2010)
De-Zolt, S., Ruiz, P., Altschmied, J., von Melchner, H., and Schnütgen, F.
Gene Trap Vectors and Mutagenesis.
Meth. Mol. Biol. 530, 1-19 (2009)
Schnütgen, F., Stewart, A. F., von Melchner H., and Anastassiadis, K.
Engineering Embryonic Stem Cells with Recombinase Systems
in Essential Stem Cell Methods (ed. R. Lanza), Elsvier/Academic Press, pp. 541-577 (2008)
Dabovic, B., Chen, Y., Choi, J., Vassallo, M., Dietz, H.C., Ramirez, F., von Melchner, H., Davis, E.C., and Rifkin, D.B.
Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity.
J. Cell. Physiol. 219 , 14-22 , (2008)
Liebner, S., Corada, M., Bangsow, T., Babbage, J., Taddei, A., Czupalla, C.J., Reis, M., Felici, A., Wolburg, H., Fruttiger, M., Taketo, M.M., von Melchner, H., Plate, K.H., Gerhardt, H., and Dejana, E.
Wnt/beta-catenin signaling controls development of the blood-brain barrier.
J. Cell Biol. 183, 409-417, (2008)
Guardiola-Serrano, F., Haendeler, J., Lukosz, M., Sturm, K., Melchner, H., and Altschmied, J.
Gene trapping identifies a putative tumor suppressor and a new inducer of cell migration.
Biochem. Biophys. Res. Commun. 376, 748-752, (2008)
Schnütgen, F., Hansen, J., De-Zolt, S., Horn, C., Lutz, M., Floss, T., Wurst, W., Noppinger, P.R., and von Melchner, H.
Enhanced gene trapping in mouse embryonic stem cells.
Nucl. Acids Res. 36, e133, (2008)
Petrova, T.V., Nykanen, A., Norrmen, C., Ivanov, K.I., Andersson, L.C., Haglund, C., Puolakkainen, P., Wempe, F., von Melchner, H., Gradwohl, G., Vanharanta, S., Aaltonen, L.A., Saharinen, J., Gentile, M., Clarke, A., Taipale, J., Oliver, G., and Alitalo, K.
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.
Cancer Cell 13, 407-419, (2008)
Bangow, T., Baumann, E., Bangsow, C., Jaeger, M.H., Pelzer, B., Gruhn, P., Wolf, S., von Melchner, H. and Stanimirovic, D.B.
The epithelial membrane protein 1 is a novel tight junction protein of the blood-brain
J. Cereb. Blood Flw Metab. 28, 1249-1260, (2008)
Floss, T., and Schnütgen, F.
Conditional gene trapping using the FLEx system.
Methods Mol. Biol. 435, 127-138, (2007)
Wegmeyer, H., Egea, J., Rabe, N., Gezelius, H., Filosa, A., Enjin, A., Varoqueaux, F., Deininger, K., Schnütgen, F., Brose, N., Klein, R., Kullander, K., and Betz, A.
EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin.
Neuron 55, 756-767, (2007)
Horn, C., Hansen, J., Schnütgen, F., Seisenberger, C., Floss, T., Irgang, M., De-Zolt, S., Wurst, W., von Melchner, H., and Ruiz, P.
Splinkerette PCR for more efficient characterization of gene trap events.
Nat. Genet. 8, 933-934, (2007)
Schnütgen, F., Stewart, A.F., von Melchner, H., and Anastassiadis, K.
Engineering embryonic stem cells with recombinase systems.
Meth. Enzymol. 420, 100-136, (2006)
Lutz, M., Wempe, F., Bahr, I., Zopf, D., and von Melchner, H.
Proteasomal degradation of the multifunctional regulator YB-1 is mediated by an F-Box protein induced during programmed cell death.
FEBS Lett. 580, 3921-3930, (2006)
De-Zolt, S., Schnütgen, F., Seisenberger, C., Hansen, J., Hollatz, M., Floss, T., Ruiz, P., Wurst, W., and von Melchner, H.
High-throughput trapping of secretory pathway genes in mouse embryonic stem cells.
Nucl. Acids Res. 34, e25, (2006)
Nord, A.S., Chang, P. J., Conklin, B.R., Cox, A.V., Harper, C.A., Hicks, G.G., Huang, C.C., Johns, S.J., Kawamoto, M., Liu, S., Meng, E.C., Morris, J.H., Rossant, J., Ruiz, P., Skarnes, W.C., Soriano, P., Stanford, W.L., Stryke, D., von Melchner, H., Wurst, W., Yamamura, K., Young, S.G., Babbitt, P.C., and Ferrin, T.E.,
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse.
Nucl. Acids Res. 34, D642-D648, (2006)
Schnütgen, F., De-Zolt, S., Van Sloun, P., Hollatz, M., Floss, T., Hansen, J., Altschmied, J., Seisenberger, C., Ghyselinck, N. B., Ruiz, P., Chambon, P., Wurst, W., and von Melchner, H.
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome.
Proc. Acad. Natl. Sci. USA 102, 7221-7226, (2005)